What condition arises from insufficient secretion of thyroxin?

The condition that arises from insufficient secretion of thyroxin is hypothyroidism. Thyroxin, which is produced by the thyroid gland, plays a crucial role in regulating metabolism. When there is not enough thyroxin, various bodily functions slow down, which can lead to symptoms such as fatigue, weight gain, cold intolerance, and depression among others.

Hypothyroidism can have multiple causes, including autoimmune diseases like Hashimoto's thyroiditis, certain medications, or congenital issues. The lack of adequate thyroxin impedes the body's metabolic processes and can have widespread effects on health.

Cushing's syndrome, on the other hand, is caused by excess cortisol production, not an issue with thyroxin. Hyperthyroidism refers to an overproduction of thyroid hormones, which is the opposite of what occurs in hypothyroidism. Diabetes Mellitus is related to insulin regulation and glucose metabolism, which again does not involve thyroxin at all. Therefore, hypothyroidism is clearly linked to insufficient secretion of thyroxin, making it the correct answer.